DPCstruct | MC686

Metacluster Properties and Pfam Annotations

Number of structural domains39
Mean domain length (aa)173 ± 15 aa
Standard deviation of domain lengths14.88
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score72.15
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)25.17
Pfam Score98.48
Assigned Pfam label(s) CL0482- PF06749

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3L6T2E7 6-181 TTIIVCSVVGSLGVLSSILGFSAEGTKLTPNDILVLGDECIYPQNPALGLGICATIFLLAAQITVTAVGGSCGCCKSRAIPSETKRI…
I1LET5 7-184 ILVLIIALHLIAFVFAVGAERRRSEAKVVPDEYDDQTFCHYTTDASTVYGLSAVALLLLSHTVLNGVTRCLCCGKGLVSGCSATSAV…
A0A5B6V5H1 5-181 None
A0A835S9H4 195-377 None
A0A835JBX1 2-173 None
A0A6J1EX08 72-233 None
A0A0E0HEZ1 1-175 None
A0A843UD42 6-208 None
A0A2G5DKK9 4-177 None
A0A803LWC0 2-149 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.