DPCstruct | MC6775

Metacluster Properties and Pfam Annotations

Number of structural domains24
Mean domain length (aa)128 ± 19 aa
Standard deviation of domain lengths19.33
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score71.39
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)34.90
Pfam Score100.00
Assigned Pfam label(s) CL0361

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Y2HF89 1-97 MLPYDLYCPSVQSVLPTRVCKHCGLYFASNIMLKKHIIGVHKITGMCQPEVGRVRPLRIAARRQQKLMAVIAFTKNVEFADWVDEDD…
A0A4C1YQI9 88-225 KFSPLLVRLSVDLSPPLEGFKQMPYDIFCSSVQFDLKNRICATCGIYFTSQKSVQTHSHSVRGKTTQDRREIRVRQQRFAASRASEL…
A0A817S773 3-159 None
A0A212EMI2 175-300 None
A0A164LH95 191-326 None
A0A164KD94 406-509 None
A0A4Y2SIR2 24-142 None
A0A4Y2LNW1 13-141 None
A0A4Y2U5K1 29-179 None
T1EP50 545-654 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.