DPCstruct | MC675

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)249 ± 30 aa
Standard deviation of domain lengths30.47
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score73.87
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)49.43
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6U4FMT1 1-259 VGGSGEIPPRQALEVFRRLLAKLDGIARALVRGAGGRELSLEALSTHETGAELREVLAGLRSLVAQVPAASRDEVALRLGQQLFKRM…
A0A453JA88 1-252 MSNDLPAGGIMDLNVMTPPPATFPDNLGSGLPDTLSTGDAMERYEQVSQKLEVLIAKDGKDVEIQSVVAEVPDILLKCVNRDEAALA…
A0A2P2MSE1 252-509 None
F6GV61 9-199 None
A0A1D6PMI2 623-873 None
A0A1D6PMF5 283-532 None
A0A287Q226 2-203 None
A0A452YUI5 229-484 None
A0A452YUD7 266-525 None
A0A452YUD2 1-242 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.