DPCstruct | MC6725

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)128 ± 7 aa
Standard deviation of domain lengths6.97
Length coefficient of variation0.05
Mean AlphaFold2 pLDDT confidence score84.98
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.85
Mean intra-cluster local Distance Difference Test score0.84
Mean intra-cluster sequence similarity (%)49.72
Pfam Score100.00
Assigned Pfam label(s) CL0126

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3T1DUX6 1-139 MTISVAEVDPVLVTTRREALEEPYRTMIGHMRHEISHMLWWRLSLRDDFLDAFREMFGDERQDYQAALQRHYQDGPPPDWKERYLTT…
M2AYV9 50-177 TGHQNGLITINLAEADSVHRERLRVKLGEPQRTLIGHMRHEVGHYIDWAWASRVAPAKYHALFGDPNTLDYGEAMKKHYAVGAPANW…
A0A2P8KF45 196-331 None
A0A6P3ZBP0 131-267 None
A0A4Q2XTL8 83-207 None
A0A7Y2HU99 3-115 None
A0A6N2DGU2 278-408 None
A0A5B8V5F4 5-131 None
A0A494XUJ4 108-233 None
A0A0S8EYM3 162-282 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.