DPCstruct | MC6677

Metacluster Properties and Pfam Annotations

Number of structural domains315
Mean domain length (aa)219 ± 51 aa
Standard deviation of domain lengths50.80
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score79.75
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)21.74
Pfam Score96.30
Assigned Pfam label(s) CL0023- CL0063- CL0669- CL0021- PF08701

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7C4GJL9 22-225 MNKSDLVPRDVLDEWVEVFRREGLKATYISARERMGTMKLRRLIKGEAPEFPAVVLVVGFPKVGKSSIINVLKGRSSASTSPIPGNP…
A0A821ZTL1 23-235 FVLNKCDLVPTWATKRWVAVLSKDYPTLAFHASLTNPFGKGAFIQLLRQFGKLHTDKKQISVGFIGYPNVGKSSVINTLRSKKVCNV…
A0A7X3T5U5 3-172 None
A0A2G6H3J8 18-212 None
A0A5J4Z5B1 165-479 None
C0AG71 71-230 None
Q4N7Y9 308-529 None
A0A7S3LWN3 2-196 None
A0A2G2X9L5 442-647 None
A0A655RKZ6 1-127 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.