DPCstruct | MC666

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)131 ± 7 aa
Standard deviation of domain lengths6.54
Length coefficient of variation0.05
Mean AlphaFold2 pLDDT confidence score85.24
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.85
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)32.08
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A423TV51 1-116 MAEGLQAFIEAIVKETVSLVISRQLLSDVSTHLTSMADHVAKTVAHFTLDKVQPRVISFEEQVASIRQHLADIYERESSWRDAAAVL…
A0A453IR84 41-170 DSALASAAAIADQRQKIEQYRHILASVISSSPPDIPQAKRFLNHMVSDEVPLVVSRQLLQTFAQELGKLEPDSQKEVAHYALTQIQP…
A0A1Y1WJV4 5-146 None
A0A2H1CIU1 6-141 None
A0A820X6A4 4-141 None
A0A6A5AZ42 3-131 None
I1CDC3 3-136 None
A0A7J8NUV2 2-129 None
A0A2S6C1A8 822-952 None
A0A6A0H3S1 11-142 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.