DPCstruct | MC6640

Metacluster Properties and Pfam Annotations

Number of structural domains6
Mean domain length (aa)56 ± 2 aa
Standard deviation of domain lengths2.13
Length coefficient of variation0.04
Mean AlphaFold2 pLDDT confidence score91.38
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.92
Mean intra-cluster local Distance Difference Test score0.92
Mean intra-cluster sequence similarity (%)49.26
Pfam Score100.00
Assigned Pfam label(s) PF12957

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A175A7W5 7-60 IKVVMLEPGKLARTAEIDASLAGMQKTVGGLIEPFYPFEEQVCIVCNEESKING
A0A174BRY8 1-54 MKVLMVEPGKSPYETEIEGGMESLQAAVGGDIQATYPFDDLVGLICNDEGKLMG
A0A3D0XA08 543-601 None
A0A3S5ATM5 286-342 None
R6MF37 532-590 None
R5S133 1-55 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.