DPCstruct | MC6557

Metacluster Properties and Pfam Annotations

Number of structural domains9163
Mean domain length (aa)194 ± 45 aa
Standard deviation of domain lengths45.30
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score80.49
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)18.48
Pfam Score95.90
Assigned Pfam label(s) CL0022- PF01412- CL0113- PF08518- CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7C4VAP0 71-264 WIALMHASYRGYIDCVRALIKAGANINVKDKDGSTPLMIASCWGYIDCVRALIKAGADVNLKNNYGWTALMYANRHGRIDCVQKLIK…
A0A521BYT4 11-193 KEGQLDNVKNLLKEGADIDETAKNGSSALIIATQYDHPELVGYLLEKGADPNKATTMGATALNRAAENGNIAVMKLLFDHGAKVGDL…
A0A654I348 58-284 None
A0A511TEI9 38-255 None
A0A2J8AC17 221-383 None
A0A2J8AFX3 258-484 None
A0A2J8AGF1 252-482 None
A0A2J8AI22 428-672 None
F4PK67 114-341 None
K2SIH9 804-999 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.