DPCstruct | MC65

Metacluster Properties and Pfam Annotations

Number of structural domains22
Mean domain length (aa)145 ± 27 aa
Standard deviation of domain lengths26.79
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score88.30
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.77
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)31.35
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A527HXN0 14-125 FSPGSQCLLTRSTDGYLRQKSAKIILPLNEPWTIPFIVLLLGEYVVEILDDIHLAMPYFDQTAYASFVRQNRQVMRAIRAKATSYWN…
A0A1G6QUU5 17-152 EELDPALERSLTGTQRVIAHCLYSRHHDGYVRQRSLELLMDSAEPWVAPFVVHLAGEYVLEILEDIRRGLGGLTVPGSVERQLYGEF…
A0A143GKS2 1-100 None
R7F464 7-147 None
A0A1Y3KM16 34-167 None
A0A519EDM2 28-184 None
A0A4R7ZAG0 28-221 None
A0A7Z2SYE6 1-118 None
A0A2G1LI36 9-223 None
A0A2N0H8J5 53-203 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.