DPCstruct | MC648

Metacluster Properties and Pfam Annotations

Number of structural domains28
Mean domain length (aa)225 ± 24 aa
Standard deviation of domain lengths23.60
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score72.09
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)22.91
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7S6W048 86-301 DKSSWIWGMLKGDFNKNPTMSQIIVSGLISMIPVVDQVCDVRDLIANLIDLSKENGKSSDNYKALALTAFGVIPEIGSAVKTIVKAA…
A0A375HI30 26-264 GLWLWEAIQGDFNEDRSAGQIAADMVISLIPIVDTICDIRVLCANIRAYRKDPGNKLILFFIALTIIGFFPEVGSVIKGVIKIAFVY…
A0A4Q4XBN7 42-269 None
A0A250IYN2 1-242 None
A0A378QIP5 109-342 None
E0SGL7 192-407 None
F3LMC2 29-276 None
E2CL44 170-431 None
B7VTR7 2-199 None
A0A837GA28 2-200 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.