DPCstruct | MC647

Metacluster Properties and Pfam Annotations

Number of structural domains16
Mean domain length (aa)139 ± 11 aa
Standard deviation of domain lengths11.30
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score70.32
Mean fraction of residues predicted as intrinsically disordered0.53
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)39.67
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1W1XVD1 1-136 MTNTTTPLELHACMGLNACKGHDRLGSNECAGSGSCATAAAHSCHTLNNCRNQGGCGLYGTGEEQDHPGDNPCAWLGSCAVPINAER…
A0A3L8KVN1 6-150 TPHTPGPQDDPPPLPQEVPRELHVCMGLNSCAGLDILGSAPMAGMGACATVHHVCHGEGACRGQGGCGYAGTEYEQFHPGEQDCRYN…
A0A4V2AGK6 6-146 None
A0A0A1FGW5 497-652 None
A0A6N9NKJ2 345-477 None
A0A2V8MPL4 2-138 None
A0A266Q992 254-413 None
A0A2E0XET2 32-156 None
A0A518E1J8 28-162 None
A0A7G8K8W3 56-194 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.