DPCstruct | MC6451

Metacluster Properties and Pfam Annotations

Number of structural domains19
Mean domain length (aa)126 ± 15 aa
Standard deviation of domain lengths15.09
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score78.97
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)26.12
Pfam Score100.00
Assigned Pfam label(s) CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0L8GFP7 11-133 LFREVAKTQTAAPVWKEITVNTGGSDSTLQDIKVSNTSGGYAYQDSTQPNSAASNRFIYWRTTGDILELVEQSLDYNLIGSHVRYRF…
A0A3Q1IRK4 3-143 MAAVLERSFIEICGFERETLHRFREVTVNLGLTALPGGAKFPDSAGAFHYEESGKLLSVTSNRFIHWSTSGDMVQLVEQSLDTNLLN…
F7AF74 4-129 None
A0A6F9DNF1 4-133 None
W2SYA6 4-123 None
A0A2P5Y3V4 1-129 None
A0A2A2KSX6 15-124 None
A0A2K6S1J1 32-190 None
A0A820Q4Z2 23-138 None
A0A0N4T7Q6 34-174 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.