DPCstruct | MC64447

Metacluster Properties and Pfam Annotations

Number of structural domains4104
Mean domain length (aa)221 ± 45 aa
Standard deviation of domain lengths45.34
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score86.79
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.41
Mean intra-cluster sequence similarity (%)12.55
Pfam Score91.37
Assigned Pfam label(s) CL0221- CL0110- CL0015- CL0316- CL0202

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A557S4V2 12-221 ISPVTLVFMGDSITEGQYVHHSLRWTEMVAKQVRLDVSRRIDSDSLHFFNRGISGETTRQGLERFPRDVQVLQPDIITIQFGLNDCN…
A0A4R6G302 43-229 KKIIESQIYPDVVFIGNSITEGWVASQPEFFKNNNYEGRGIGGQTTPQMLIRFIPDVVNLQPKAVVILAGTNDIAGNTGFSSVEMIT…
A0A2A7R253 2-197 None
K8FD72 122-400 None
K8FAU0 286-544 None
A0A6L3EU24 92-388 None
K8EA43 5-225 None
A0A6J1ECZ4 681-982 None
A0A5B7E0I3 1-140 None
A0A6L3F537 258-484 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.