DPCstruct | MC64413

Metacluster Properties and Pfam Annotations

Number of structural domains94
Mean domain length (aa)176 ± 36 aa
Standard deviation of domain lengths35.51
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score82.39
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)14.38
Pfam Score96.15
Assigned Pfam label(s) CL0023- CL0105

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A174SX57 6-158 YNPEEILGTVESVDTSTAIIKVENDDKLRGLQVNHLVAIQSSKVDQHLIGLVSKIIRKSGYSDPIAEVTPEFAFNVIKVVLIGTHLD…
A0A0S8KE35 1-166 MRIGEIVETMSTGFVAESFELNRPPPLGSLVVVRLPAEAGETSSGMDLYAVVTYGQTVGLDPSRRAVRRSTDTVFDQAIYQEHPELN…
A0A833E815 16-152 None
A0A7W5S4P5 21-210 None
A0A0P7HEC7 44-259 None
A0A5N9AJV4 1-146 None
O66421 36-243 None
A0A7V9TUP8 121-263 None
A0A535Y7S9 379-533 None
A0A2C6M7F0 12-125 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.