DPCstruct | MC64368

Metacluster Properties and Pfam Annotations

Number of structural domains10
Mean domain length (aa)89 ± 13 aa
Standard deviation of domain lengths13.04
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score85.49
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.86
Mean intra-cluster local Distance Difference Test score0.90
Mean intra-cluster sequence similarity (%)53.74
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4C3QB63 1-95 MLAILVVQTIFMALYAIFVTWRMMGKNYDAAVLAAGHCGFGLGATPTAIANMQAITERFGPSHMAFLVVPMVGAFFIDIVNALVIKL…
W1EX18 222-337 LFLAMALMGLKLWELASLALPMLAILVVQTIFMALYAIFVTWRMMGKNYDAAVLAAGHCGFGLGATPTAIANMQAITERFGPSHMAF…
A0A3A5K858 224-300 None
A0A2X4V4V7 1-66 None
H1D946 65-161 None
A0A2N9LZP7 86-172 None
A0A8B6KSC3 46-133 None
A0A354KSQ8 142-231 None
A0A447T8D8 144-237 None
R5G6S9 3-78 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.