DPCstruct | MC64312

Metacluster Properties and Pfam Annotations

Number of structural domains4386
Mean domain length (aa)203 ± 53 aa
Standard deviation of domain lengths52.79
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score77.95
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)17.66
Pfam Score87.99
Assigned Pfam label(s) PF19788- CL0681- PF05231- PF06580- PF19191

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7R6XM89 16-179 STEQGERLARAAMLVDQLSTRVHAAAWNLRPADLDHLGLRASVEDLAAMLCAQLDIPCDMDLEALSCPLAPEVALTLYRVAQEALTN…
A0A7V9P4L7 1-117 RLESVDSLGLARAAAAELEDGTVRVSGEGAPVSVEPDATRRALRQLSRAARRHGGLESVELRVRGAELELGPITRTAGVVVTGEELR…
A0A538PX25 544-758 None
V4IVX4 118-343 None
A0A538Q684 449-706 None
A0A5J6F057 13-153 None
A0A3M1BV61 2-361 None
A0A1M3F9P4 2-97 None
A0A7G6E7A4 176-409 None
A0A4Q5L1V3 320-561 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.