DPCstruct | MC6427

Metacluster Properties and Pfam Annotations

Number of structural domains225
Mean domain length (aa)195 ± 34 aa
Standard deviation of domain lengths33.85
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score85.18
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)29.60
Pfam Score98.39
Assigned Pfam label(s) CL0260- CL0598- CL0037

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A256H1B0 2-145 IAVEDPNYSTHSGVDFSTPGAGLTTITQSAAKRLAFEQFHPGPGKIRQTGYALGMERRLSKEQILALWLETLEMGKGPDGWIVGFHS…
A0A6I6DFG9 35-242 WDNPEPLYLENIKIEKVGDSLVLGYTERNIKYVELHDIPQDLINAFIAIEDNRFFQHRGVDVKGVIRAIAVNIYFKELAQGGSTITQ…
A0A7C1RT88 6-135 None
A0A537THJ2 38-262 None
A0A6G8G1R7 81-247 None
A0A1E3G1V6 35-255 None
A0A1A9UKJ3 2-171 None
A0A6G3V974 1-130 None
A0A812IYI2 284-478 None
A0A3C1KWU0 729-886 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.