DPCstruct | MC64268

Metacluster Properties and Pfam Annotations

Number of structural domains90
Mean domain length (aa)124 ± 18 aa
Standard deviation of domain lengths17.76
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score83.91
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)31.50
Pfam Score75.73
Assigned Pfam label(s) PF04446- PF14413

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0B1PRW3 372-486 TLKRPPCFDGRAVLYPNDATMMDYLKWRQADCHINNLYNTAFWKLVLELGWTCAEAQARLRGSTSADKNELLFSMFNTNYNNEPQLF…
A0A4Q2YVE6 3-130 VFDCRMIPLPSEVEVVEYFRWRAEDARRNCLNAHCYWTLRNKENSASAATEAIRYLAAAEKVDLLRREAGMEFEALPSWQRNGVGLR…
A0A443NEE5 151-286 None
A0A2V1D8A1 146-255 None
A0A834MZG3 146-267 None
A0A1T3P8D4 346-462 None
A0A654HHB8 566-667 None
A0A3D3LGS6 130-250 None
A0A5J5VRG7 138-258 None
D5HGM8 1-118 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.