DPCstruct | MC64252

Metacluster Properties and Pfam Annotations

Number of structural domains984
Mean domain length (aa)157 ± 32 aa
Standard deviation of domain lengths31.82
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score85.15
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)25.29
Pfam Score99.14
Assigned Pfam label(s) CL0475- PF10585- CL0063- CL0046- PF02271

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A521K971 6-154 NTNQGAIVIEFFGDDAPNTVENFKKLAESGYYNGTKFHRVIPGFMVQGGDPFTKDDSLSGKWGTGGPGYTFEDEIHANNKNDIGTIS…
A0A419G6M9 5-119 PELMPVTAGNFEKLVQSNFYDGLVFHRVEDWVIQGGDPKGNGTGGPGWTIPLETSPKLKNVRGAVAMARSKNPDSAGSQFYILKKDA…
A0A7S2UKX2 80-281 None
A0A654HG56 712-835 None
A0A7S4E4Q0 204-365 None
A0A7S3ZWC5 17-196 None
A0A6P5GAU1 85-209 None
A0A5N4A7L9 127-285 None
A0A522XAJ4 4-194 None
A0A7C1KWU9 2-110 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.