DPCstruct | MC64158

Metacluster Properties and Pfam Annotations

Number of structural domains166
Mean domain length (aa)107 ± 19 aa
Standard deviation of domain lengths19.46
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score86.43
Mean fraction of residues predicted as intrinsically disordered0.39
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)27.47
Pfam Score83.33
Assigned Pfam label(s) PF21157- CL0167- CL0382- PF21173

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7K2IXB3 19-134 TPEELAEVRGLLEIEIEVRKAELRENEDEVAERLTDPVEGAGDDPADVGAKAFQREHDLALAYNTRDLLAMSERAIERMDAGTYGAC…
A0A2D0IGD2 5-101 LAQIELALVESVSATATVMLDQSSVGRLSRMDALQQQALAQEMRGRLQLSKRKLEAAMVRLDAGRYGLCCDCGEPMEADRLDRDPAA…
A0A7X0LT08 173-283 None
T0D0U9 2-61 None
A0A0H5D3X8 30-106 None
A0A4R8CT56 7-125 None
D9SKL3 6-126 None
A0A838E504 8-121 None
D7N2S0 4-97 None
A0A3B9PUK0 51-161 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.