DPCstruct | MC64056

Metacluster Properties and Pfam Annotations

Number of structural domains872
Mean domain length (aa)156 ± 31 aa
Standard deviation of domain lengths31.03
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score77.06
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.37
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)20.81
Pfam Score92.47
Assigned Pfam label(s) PF16046- PF16182- CL0126- PF03763- PF03535

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7E4RFD2 24-165 FAVEQNRPYCNPCYLVLFGKKCKRCGELIEKSKTIAALGVHWHLEHFTCESCKTELNQKQFFEKDGMPYCKDCYEKKFCPTCKGCKK…
U5CPH3 14-174 ISCTHCGRWISEDEVHYGADHYPYCEECYDKLFINCTYCGETVWKEDAKRTPDDEYICSNCFNEHCVSCTECGKTLYKDEAEYVNNE…
A0A5S6Q6Q4 2-99 None
A0A6I8VX77 68-240 None
A0A397FFE6 348-491 None
A0A1V8T0J9 608-793 None
A0A7E4WDE1 92-196 None
A0A5B8SCW3 3-128 None
A0A2I2YL09 2-169 None
A0A3Q7SY39 117-281 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.