DPCstruct | MC64018

Metacluster Properties and Pfam Annotations

Number of structural domains200
Mean domain length (aa)137 ± 20 aa
Standard deviation of domain lengths20.46
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score84.79
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)20.89
Pfam Score99.13
Assigned Pfam label(s) PF01124- PF05821- CL0263

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A523MH56 6-126 YTALVTIAAVVYTFILSGFVSAARAKTGVNAPAMAGQPDFDRVFRIHMNTVEQLVLFIPVLWLATSVVGDLWAAEIGVVWIVGRLTY…
A0A6J0SU66 2-111 VSKAYFALQVISVRRKCKITPPLTLGPPEFERIFRAQTNCSEYFPIFISLLWVSGIFSHQVLAAFCGLLYLYARYWYFTGYARSAQE…
K8FHW7 18-159 None
A0A1W9I0Z8 1-128 None
A0A819R6G2 358-473 None
A0A812Y2J3 307-467 None
A0A7S2KV36 5-142 None
A0A835GZ67 2-107 None
A0A2G2J3P5 92-221 None
A0A7S1XV94 75-239 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.