DPCstruct | MC64005

Metacluster Properties and Pfam Annotations

Number of structural domains166
Mean domain length (aa)159 ± 30 aa
Standard deviation of domain lengths29.75
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score70.68
Mean fraction of residues predicted as intrinsically disordered0.38
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)24.97
Pfam Score96.21
Assigned Pfam label(s) CL0123- CL0229- CL0114- CL0029

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7J8N0Z7 14-160 MKEPVSSYTSYPPPLARYEDVVASPKLFLATLEKLHATMGTKFMIPVIGGKELDLHKLFVEVTSRGGIEKIVRERRWKEVTAVFNFP…
A0A3P7DPL1 72-196 IDRLVGPVTAMNPQHIMPERRAFFEKLVQFCEQQGEPITQVPQVSKQTVDLHRLYLAVMKRGGFEQVTRDKTWKQVCTEANSEMSES…
A0A5K4FB54 578-758 None
A0A2G3B4J4 7-163 None
G4LUD8 12-209 None
A0A5N6PJU3 67-269 None
A0A396HZN8 9-169 None
A0A5B8MK90 50-196 None
A0A3B4DTU9 12-167 None
A0A4Y1R0C2 7-191 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.