DPCstruct | MC640

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)185 ± 10 aa
Standard deviation of domain lengths10.19
Length coefficient of variation0.05
Mean AlphaFold2 pLDDT confidence score74.07
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)24.16
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A285TU41 129-313 GASSEGPLACILRNVEVNLVPVFIDVAFAFMVLFGVFMIAKSIYSMAVSHAQGQRGQGANWQGNLILGIILTNLPAFLHTIEETLGV…
A0A1G0G2G1 2-178 RVDPTFPELLHNLAVALPAVGKLVAAAMYLAGFVLIFRGLYALKQYGEMRTMMSVNADLKTPIILICIGTVLIFYPTLINTSLSTVY…
A0A1J4RH97 201-375 None
A0A2S5MFF7 11-184 None
A0A1R3L1I0 221-417 None
A0A142BW95 15-185 None
A0A3M3JU98 25-216 None
A0A2D6K2Y3 376-573 None
K2CF95 22-216 None
A0A2D8M2J2 169-362 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.