DPCstruct | MC63996

Metacluster Properties and Pfam Annotations

Number of structural domains58
Mean domain length (aa)100 ± 14 aa
Standard deviation of domain lengths14.08
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score90.78
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.86
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)40.89
Pfam Score100.00
Assigned Pfam label(s) CL0257

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6C1RI98 531-615 GAQLIGAGWVDVLPRGLSSVYYVFDPHYAARSLGVFSVLREIELAAQLNKEWLYLGFFVPGCPSMSYKANYHPYDLLIGGRWHRW
A0A149VFH5 5-87 QLVCVSLVDVMSDGLSAVYTFYDPTTPAASWGTFSILWLLHLAKQRGHLHLYLGYYVPGSQKMAYKATFQPAEIFQGGHWTLL
B6K0Y7 214-299 None
A0A7C3TLK2 173-262 None
A0A2E8X8A1 59-159 None
A0A183J8N5 39-124 None
E1ZK19 49-153 None
A0A4Z1PGY4 269-376 None
A0A7C8QJ80 143-231 None
A0A072PDD2 95-223 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.