DPCstruct | MC63991

Metacluster Properties and Pfam Annotations

Number of structural domains23
Mean domain length (aa)251 ± 33 aa
Standard deviation of domain lengths32.86
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score83.62
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)24.30
Pfam Score100.00
Assigned Pfam label(s) CL0490

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A149SEE8 20-242 IGHILFLSDSILFTRTDMSGPLLTREHVDFSPRDGHFLRHVLLPTPVTHAQQLMEGLHFARWTGSGLRWMYFLSGVLGAVMFGSGSV…
A0A7C7Q6B3 147-417 LINILVLVAAPLLFEGDREAVVAAVYGADPVMKTEQHTFDIEKAMVELQRVASEATPIYLAFHQPGSDKQFLEIAATLPGRLVFSEI…
W5Y8C4 25-290 None
A0A2G2H3M6 2-264 None
A0A1W1IA47 215-398 None
F7SXJ7 126-385 None
A0A199P186 1-222 None
A0A3R8VDL3 54-323 None
A0A316MXI0 315-596 None
A0A0Q4CAQ3 2-212 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.