DPCstruct | MC63950

Metacluster Properties and Pfam Annotations

Number of structural domains265
Mean domain length (aa)277 ± 53 aa
Standard deviation of domain lengths53.17
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score90.68
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)18.16
Pfam Score78.92
Assigned Pfam label(s) PF00384- PF18364- CL0344- CL0109

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7H4MMG0 7-271 TWETQQTDYPRTRPDLPNHEPRGCPRGASYSWYLYSANRLKYPLMRKRLMKMWREAKVQHSDPVEAWASIIEDADKAKSFKQARGRG…
A0A4P0YBI4 2-276 QFAPSICQQCSIGCNISPGERYGELRRIENRYNGTVNRYFLCDRGRFGYGYVNLKDRPRQPVQRRGDDLITLNAEQAMQGAADILRQ…
A0A7Y4J0Y2 95-361 None
A0A2T2UI81 54-391 None
A0A379FIL2 38-287 None
A0A3B4E335 247-585 None
F6DF47 20-404 None
A0A5C7N2P0 9-338 None
A0A6J7RHG9 4-334 None
A0A3M1I7G5 2-269 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.