DPCstruct | MC63895

Metacluster Properties and Pfam Annotations

Number of structural domains167
Mean domain length (aa)99 ± 17 aa
Standard deviation of domain lengths16.67
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score87.77
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)21.77
Pfam Score98.86
Assigned Pfam label(s) CL0042- CL0161

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Q7W290 126-214 EPDRLHRGLQGARFTATTLAGVRRRGWSQSVAEREQGVASVSAPVRGPNNRVIAAVSVSGPIERLTRQPGRLHAQSVVEAAARLSEA…
A0A268HXN9 14-105 PEEQRVDYLEHVLLKPITPHTITDKETLLARLQEYEQLGYAIDDEENEEGLYCVAAPIFDASKVMQAAISVAGPKERMLRQKSQIVN…
A0A2S8U0S1 64-148 None
A0A7X5WWM8 4-99 None
A0A516PVS6 112-214 None
A0A2E2RK33 58-187 None
A0A248UNN9 143-249 None
A0A7W1J435 75-162 None
A0A349WC40 21-114 None
A0A1H0V1E4 204-316 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.