DPCstruct | MC6385

Metacluster Properties and Pfam Annotations

Number of structural domains67
Mean domain length (aa)153 ± 30 aa
Standard deviation of domain lengths30.21
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score79.30
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)22.39
Pfam Score90.91
Assigned Pfam label(s) PF03461- CL0408- CL0065

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A380FDC0 4-106 KDELIDRFNEYPVEVERLLDMMEIKVHALHAGVTLIKDTGKQVEVYMSEKGTTEINGESLFKHTQPLGRAMKVGVQDGKMKVTLNKT…
A0A7Y3FJY5 13-172 MFVQMLNEAVAELKGEPLQPEIDPELSVEIEHYLPEEYIDDIGLRLSLYRRFATAVDEAAVDELAMEMEERFGAPPPPARAFIRLMS…
R6H943 7-206 None
A0A7V1ZDE8 1-123 None
A0A540VK97 1047-1242 None
Q2HRW7 12-143 None
A0A376F4X1 4-134 None
A0A7N2KZ43 455-592 None
A0A656KAV3 1-104 None
A0A1A2XIX5 3-120 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.