DPCstruct | MC63798

Metacluster Properties and Pfam Annotations

Number of structural domains3007
Mean domain length (aa)266 ± 71 aa
Standard deviation of domain lengths70.57
Length coefficient of variation0.27
Mean AlphaFold2 pLDDT confidence score81.65
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.42
Mean intra-cluster sequence similarity (%)13.32
Pfam Score78.01
Assigned Pfam label(s) CL0110- PF04852- CL0219- CL0111- PF05699

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2A2NXK5 10-226 None
A0A377TM34 128-333 None
A0A7X1U4J0 2-397 None
B0WHP7 150-407 None
A0A5C2ESC5 9-227 None
I0IKQ5 3-137 None
A0A287B6A4 480-720 None
Q2RTK4 20-260 None
A0A6J8D3Z7 96-467 None
A0A4Z1H945 7-276 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.