DPCstruct | MC63798

Metacluster Properties and Pfam Annotations

Number of structural domains3007
Mean domain length (aa)266 ± 71 aa
Standard deviation of domain lengths70.57
Length coefficient of variation0.27
Mean AlphaFold2 pLDDT confidence score81.65
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.42
Mean intra-cluster sequence similarity (%)13.32
Pfam Score78.01
Assigned Pfam label(s) CL0110- PF04852- CL0219- CL0111- PF05699

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A353NMS3 27-271 KKFIRWSPETSLESIGPLDVAEFKRYLQKQGQKPATINRALATLSTFFDWAVDKGLIENNPASNVKYVKEVETAPKSLFRREQLALM…
A0A8B6B4L2 7-207 YAKQNAQRPKVRKNTETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFYIAIQDDCVRKNPFD…
A0A0F9NJ89 3-141 None
A0A0F9NY90 42-241 None
R6YJM5 455-725 None
A0A834XZB2 11-330 None
A0A1M3PCZ6 174-485 None
A0A1P8WNT1 133-518 None
A0A175Y4P8 724-1035 None
A0A417KLW3 54-411 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.