DPCstruct | MC63783

Metacluster Properties and Pfam Annotations

Number of structural domains389
Mean domain length (aa)131 ± 22 aa
Standard deviation of domain lengths21.77
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score81.12
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.37
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)14.94
Pfam Score78.03
Assigned Pfam label(s) CL0123- PF19934

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1G2CBZ5 455-581 GWVTNKNLAESLGVSERTVSAKVHKYRDGHPDWFLAYRGKKGRVFEHFHPDLIEIVSSEIKEFERAPEGWMPNGRLAHEIHRGTETI…
A0A1H1H643 5-118 DFITLTRAGRILSRDPRTVASMIRRGELAAFEVAGRRVVKESDVRALLNPVPVATQRLSLSPSRAGKRLGMSTSTVTRRVHDGELAG…
A0A1H1TR85 296-454 None
A0A254Q5D6 1-104 None
A0A6M5F9G2 1-198 None
A0A5K7XGY5 8-141 None
A0A1Y5R7N7 441-550 None
A0A5C8SMH6 699-830 None
A0A2W1UPB4 13-151 None
A0A1Q9PTP7 363-495 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.