DPCstruct | MC63716

Metacluster Properties and Pfam Annotations

Number of structural domains60
Mean domain length (aa)231 ± 35 aa
Standard deviation of domain lengths35.05
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score71.95
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)35.51
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A453KS19 5-236 TSIFDLHRSCPNCSYELCIACCKELRENNLKGSCREELVSYPHRGIDYMHGGDPSPELMNCVQTDLSSCQPKTTKWCANTDGTINCP…
A0A446QFY8 158-365 DARCYCNYCRTCIVDLYRGCECGHYDLCLSCCQELRDGSLVKKDKKLRAKPNGSILCPPKAAGGCRCRGHALKLKGIFKENFISDLL…
A0A438DKW3 304-552 None
A0A1U8P1N7 2-194 None
A0A1U8NNU2 15-254 None
A0A4Y7LDT4 18-237 None
A0A0A9DHT5 1-212 None
A0A2K3P1A2 275-529 None
A0A7J0E8F6 395-640 None
A0A7J7MEQ1 529-739 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.