DPCstruct | MC63715

Metacluster Properties and Pfam Annotations

Number of structural domains22
Mean domain length (aa)247 ± 51 aa
Standard deviation of domain lengths51.07
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score84.96
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.83
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)52.45
Pfam Score93.81
Assigned Pfam label(s) PF08082- PF08083

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A453KQ92 1-201 MWIMMRREKRDRRHFKRMRFPPFDDEEPPLDYADNLLDVEPLEAIQLELDPEEDGAVYKWFYDHKPLVKTKLINGPSYRKWHLSLPI…
A0A3P7EFR5 2-267 PHAVLKLLENMPMPWEQIRDVKVLYHITGAITFVNEIPRVIEPVYMAQWGTMWIMMRREKRDRRHFKRMRFPPFDDEEPPLDYADNI…
K0TGJ8 349-709 None
B8C3V5 550-888 None
A0A512UK03 169-449 None
S9UW48 92-374 None
U6LXD5 21-285 None
J9E1P4 1-202 None
A0A2S4VAW8 1-160 None
A0A0C2ZSK1 6-166 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.