DPCstruct | MC63699

Metacluster Properties and Pfam Annotations

Number of structural domains3594
Mean domain length (aa)187 ± 34 aa
Standard deviation of domain lengths34.08
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score84.22
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.39
Mean intra-cluster sequence similarity (%)13.19
Pfam Score96.66
Assigned Pfam label(s) CL0055- PF02672- PF01018- PF11957- PF00719

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A6QQF3 462-661 None
A0A2Z6QNB3 1-146 None
A0A3E4YLH8 3-177 None
A0A667Z4H0 31-230 None
A0A3D0ZQJ8 50-290 None
H0R2I0 237-421 None
A0A846AS20 3-208 None
A0A1Y2C4T6 527-696 None
A0A1Y2CBJ4 107-312 None
A0A1Y2CBI8 579-758 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.