DPCstruct | MC63699

Metacluster Properties and Pfam Annotations

Number of structural domains3594
Mean domain length (aa)187 ± 34 aa
Standard deviation of domain lengths34.08
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score84.22
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.39
Mean intra-cluster sequence similarity (%)13.19
Pfam Score96.66
Assigned Pfam label(s) CL0055- PF02672- PF01018- PF11957- PF00719

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2H5RAA2 4-195 None
A0A445A925 122-267 None
A0A496UNP4 5-186 None
A0A2D5ILA4 1-170 None
A0A6L5DK17 3-206 None
A0A225WVX3 318-543 None
A0A225X4E1 672-873 None
Q8C8U8 583-779 None
A0A7J6Z152 241-447 None
A0A3M5QW76 48-227 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.