DPCstruct | MC63699

Metacluster Properties and Pfam Annotations

Number of structural domains3594
Mean domain length (aa)187 ± 34 aa
Standard deviation of domain lengths34.08
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score84.22
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.39
Mean intra-cluster sequence similarity (%)13.19
Pfam Score96.66
Assigned Pfam label(s) CL0055- PF02672- PF01018- PF11957- PF00719

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3M2M7C3 446-657 None
S2KSQ0 468-646 None
A0A1Q3SMW0 198-409 None
A0A7Y9GV47 1-122 None
A0A1Q3T1P9 114-331 None
A0A2C6WG08 2-120 None
A0A2H0DPX0 42-299 None
A0A662D9W8 84-283 None
A0A1M2VQZ1 688-932 None
A0A4Y7KFK8 2-142 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.