DPCstruct | MC63699

Metacluster Properties and Pfam Annotations

Number of structural domains3594
Mean domain length (aa)187 ± 34 aa
Standard deviation of domain lengths34.08
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score84.22
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.39
Mean intra-cluster sequence similarity (%)13.19
Pfam Score96.66
Assigned Pfam label(s) CL0055- PF02672- PF01018- PF11957- PF00719

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
I4ITK0 21-151 None
A0A0Q8PMB5 8-125 None
A0A0Q8P6V6 10-197 None
A0A4Z2EG68 9-187 None
A0A1F5TSB9 4-235 None
C1MNK6 6-214 None
A0A6A2YKD1 12-269 None
A0A7J7IKD0 899-1137 None
A0A7J7IKL2 189-406 None
A0A7J7IKR1 22-239 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.