DPCstruct | MC63673

Metacluster Properties and Pfam Annotations

Number of structural domains20
Mean domain length (aa)145 ± 19 aa
Standard deviation of domain lengths19.05
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score88.78
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)25.95
Pfam Score100.00
Assigned Pfam label(s) PF20373

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A495MYL7 18-190 VAAPGPAVWLLGAHGGAGVSTLARYWDFAEDARHQWPCGDARETESPYVVVVCRETIQGLSSAHDLILEHRNRGLACELLGLVTVAN…
A0A2N7S1J6 2-134 GLHGGAGASTLASLLGDGASEVGQAWPISQNAWTGSAWPIPVIAVARTDHSGLATADRFVRSWANGQLTGSQLSALVLIEAGPRTSD…
A0A6N9VSX6 16-141 None
W8HBN6 5-154 None
A0A1R4IZ64 30-182 None
A0A853DQY9 45-207 None
A0A1Q9SJV1 1-141 None
A0A7W5VCX2 10-117 None
A0A1Q8XG01 38-198 None
A0A2A3HVH1 51-198 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.