DPCstruct | MC63670

Metacluster Properties and Pfam Annotations

Number of structural domains28
Mean domain length (aa)125 ± 16 aa
Standard deviation of domain lengths15.65
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score79.48
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)36.72
Pfam Score97.73
Assigned Pfam label(s) PF11267- CL0108

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
I0Z4D4 7-119 RLSRTFETPSISGQELRDLIVEKWGRSYDTRLHKRGQRMYLQIMWKFLEQRSFHLNENEYQAQLDAVAEYLTLWRVGPTVRAAIRSA…
C1MRS7 1-103 MTGEELRMLVLNKWGKMYDTRIHQRRDQFNKLGLYLQIMWKHVGQKSFPMTEQQYVEQLSAVAELLTEWGAQDVVRQKLPQSTKFPK…
A0A7R9Y456 8-126 None
A0A0A2BJX6 40-138 None
B8C2G8 149-280 None
A0A118JXQ8 69-241 None
A0A383VWH4 181-306 None
A0A835Y757 17-163 None
A0A5B8MIM6 95-210 None
A0A835IRX7 143-263 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.