DPCstruct | MC63669

Metacluster Properties and Pfam Annotations

Number of structural domains49
Mean domain length (aa)168 ± 24 aa
Standard deviation of domain lengths23.88
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score77.71
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)25.60
Pfam Score98.44
Assigned Pfam label(s) PF05981- PF16166

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Z4RNE6 3-155 NPQISTQDRSFGALIYLFPLVYALPFGIPLLSQFPPLAQFFSPLITLYRLTNSLPFASLIIFFGLWLGVVRNENVSYFLRYNAMQAI…
I0Z0D6 143-299 AAVPTGNRGPPSLLVRLASAFLYIVPWIDILTLGREIYHFFPTSLLLYLVPGPLAPLYYSGQFVPLIVFFLLFLAIVKNNKLHHFVR…
A0A540MBR0 278-457 None
A0A7R9Y4P9 66-258 None
A0A1Q9E7B6 590-733 None
A0A6A2XKM2 35-222 None
A0A444XAE6 421-634 None
L0AY35 738-928 None
A0A343KP80 6-166 None
A0A7J7IDD5 53-245 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.