DPCstruct | MC63643

Metacluster Properties and Pfam Annotations

Number of structural domains66
Mean domain length (aa)86 ± 6 aa
Standard deviation of domain lengths6.44
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score90.92
Mean fraction of residues predicted as intrinsically disordered0.52
Mean length-normalized TM-Score0.88
Mean intra-cluster local Distance Difference Test score0.88
Mean intra-cluster sequence similarity (%)52.53
Pfam Score100.00
Assigned Pfam label(s) CL0318

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A453RRP1 4-85 IRRGHQVYQQVCASCHSMSLISYRDLVGVAYTEEETKAMAAEIEVVDGPNDEGEMFTRPGKLSDRFPQPYPNEQAARFANGG
A0A813BVD5 1-84 VYKEVCASCHSLNRIAYRNLVDVCFSEKEAKHLAAQIEVTDGPDDTGEMFERPGKLSDYFPAPYANEEQARAINNGAYPPDLSL
A0A5J5U4S7 48-140 None
A0A443NYB3 6-88 None
A0A090MNH0 453-530 None
A0A066W1F8 135-223 None
E9G9E0 41-128 None
G6F0W2 1-66 None
A0A3P6RSG5 13-87 None
A0A059APG2 212-298 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.