DPCstruct | MC63640

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)102 ± 9 aa
Standard deviation of domain lengths8.61
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score86.88
Mean fraction of residues predicted as intrinsically disordered0.16
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)47.89
Pfam Score100.00
Assigned Pfam label(s) CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A453RHR7 1-91 MDCSILKIWNLNAHSGVIGAFNCQGAGWCREGKKNLIHDVQPGTITGAVRGRDVSRLQEVAGDGWNGDVVVYSHVAGKASFNQNQRV…
A0A6A3AFN6 532-639 GRPTVDCLFVDPARDGISLLKMWNVNKCSGVVGVFNCQGAGWCKISKKTRIHDASPDTLTGSVCANDVDSITQIAGADWNGETVVYA…
A0A6A6MKN7 309-399 None
A0A4D6MPM3 541-647 None
A0A7J7N5A9 1-115 None
A0A2Z6MWQ6 306-412 None
A0A317Y6M9 273-360 None
A0A445AAQ5 551-655 None
A0A7J6X146 959-1067 None
A0A388K2K3 946-1054 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.