DPCstruct | MC63634

Metacluster Properties and Pfam Annotations

Number of structural domains7
Mean domain length (aa)126 ± 7 aa
Standard deviation of domain lengths7.13
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score63.67
Mean fraction of residues predicted as intrinsically disordered0.40
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)33.73
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A453RDK7 1-126 MWLAGCRRCPRSYHLDCLPREICFKYGNGGIRAWFLSERNLSKRLIIYCTDHEIDPAMGTPCRDHIKFPALLENKGHGSTESTKFQH…
A0A453KCS1 1-143 MQFAVCRRCPTVYHRKCLPRDISLIEDEEEATPQRAWDGILPDQILIYCRKHEIQEELGTPKRDHIVFPDVRNPGAAERHRGAPQRH…
A0A0K9R2P0 105-230 None
A0A2R6QT91 368-487 None
A0A6A1UJS0 308-429 None
A0A7J6VIV7 70-195 None
A0A811M4C6 67-188 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.