DPCstruct | MC63623

Metacluster Properties and Pfam Annotations

Number of structural domains6
Mean domain length (aa)91 ± 7 aa
Standard deviation of domain lengths7.25
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score81.16
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.87
Mean intra-cluster sequence similarity (%)46.79
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Y2SDE7 1-85 MANKIESRISYKTLFNDNQDLYCFPNLPEANDGPLAYLVDLYQQVRLFESVADKDGSLFLSQRRPDIDKLLLDSPKIKQKMMFSI
A0A2S8Q5F6 1-98 MANKIESRINYKTLFNDNQDLYCFPGLPEANDGPLAYLVDLYQQSCLFEEDADKKSARLLSQRRPDIEKLLLDGANLNQTSQSLPLV…
A0A3M3ZFI0 6-90 None
A0A1T2Y4V4 83-186 None
A0A2D0KYY1 1-86 None
A0A3M4L2W0 1-90 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.