DPCstruct | MC63590

Metacluster Properties and Pfam Annotations

Number of structural domains9
Mean domain length (aa)523 ± 86 aa
Standard deviation of domain lengths86.36
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score84.97
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)27.98
Pfam Score71.83
Assigned Pfam label(s) CL0198- PF08354- CL0050- PF17951

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
X8AZ64 1-557 MPIDGILVGTAAMATLESTTSPSVKRMLVETQGTEHWIGAGKAVGGMASSRSQLGADIHEIDNSASRCGRLLDEVAGDAEAVAERRD…
A0A2S8BGH0 147-559 LAYGFPLMPVDGILVGTAAMATKEATTSPSVKQMLVETQGTDQWISAGKAQGGMASSRSQLGADIHEIDNTASRCGRLLDEVAGDAE…
X8F2H4 224-695 None
B8NVJ6 299-843 None
A0A401H1S2 1-651 None
M2XHU6 656-1277 None
A0A1Y1W708 679-1101 None
A0A5E3XCX6 12-437 None
A0A409Y503 130-724 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.