DPCstruct | MC63469

Metacluster Properties and Pfam Annotations

Number of structural domains50
Mean domain length (aa)173 ± 28 aa
Standard deviation of domain lengths27.93
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score77.02
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)22.58
Pfam Score97.22
Assigned Pfam label(s) CL0020- CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Y2MLC9 520-700 MKQHEMLLSDMRQVVQEEVKKALREQTTAVLNSRSTTPVPHADPQFQKQQLMQLVKQGNINEAFQQALSAMDVQLVLFLCESVNVDL…
A0A2R7WKM7 5-127 GQYNTAFQQALSASDLSLVTYTCERVDVSKVFTRNGCVLQQHVLLSLIQQLSADMSAHVEIKLRYLEAAVMSLMPNNENTRDHMPQV…
A0A0A9LI19 39-220 None
A0A6A1UUK8 40-206 None
A0A1N6LX93 542-748 None
A0A7S1SIN9 71-269 None
A0A3Q0KLN6 1362-1536 None
A0A0P0VNW0 169-350 None
A0A7C9DH35 147-311 None
A0A0A9D7F3 721-901 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.