DPCstruct | MC63466

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)122 ± 5 aa
Standard deviation of domain lengths5.40
Length coefficient of variation0.04
Mean AlphaFold2 pLDDT confidence score82.99
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.87
Mean intra-cluster sequence similarity (%)49.71
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A376DF91 21-128 GWRYTNIGVIRSENTESEFRNLYMCEFVRDGEAAFSLSALTGCGVDGYDEWPDWKPFAARPMGVREVWLGYDANGSSGKGDCGALSV…
Q8XY24 351-471 NLFDLDQLRLEYSEPEFANLLMCAFIDDNASVFPLSMLMRGMVDSWEAWEDFRPFAPRPFGNRPVWVGYDPNGGGGDSAALVVVAPP…
A0A4D0PW75 34-157 None
A0A376YLL5 146-265 None
A0A2X4DAR8 127-250 None
A0A485B863 5-135 None
A0A0N1JQ37 176-299 None
A0A2X2S3X1 1-118 None
A0A377CZB1 333-455 None
A0A3M5W0E3 94-216 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.