DPCstruct | MC63455

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)150 ± 14 aa
Standard deviation of domain lengths13.59
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score78.93
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)26.75
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A226DH09 43-192 GRDEISKLQQRAMLPRGTCWKSALEDLSVSCKGMIPEHQSRLAFKFTTCYNEMVGFPSVICERNMAIPDCMKSLDVSSQGTFREFFL…
A0A2P6VHM4 49-204 EGQVQLESLSERAAAEGFLDRLLGTNCFSTAVQELNADCRRMDQEAKTRLALRLANCQMATQGGPTHHCAPRQPLKECIEALPERVY…
A0A834LDR4 48-223 None
A0A5J4Z046 27-184 None
H3AND1 8-160 None
M0ZKA9 6-145 None
A0A4U5QLZ6 60-210 None
A0A7J7HIH0 5-121 None
A0A812I917 784-931 None
W5NBV2 1-154 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.