DPCstruct | MC63442

Metacluster Properties and Pfam Annotations

Number of structural domains41
Mean domain length (aa)604 ± 99 aa
Standard deviation of domain lengths98.51
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score83.53
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)33.25
Pfam Score73.32
Assigned Pfam label(s) PF03726- CL0329- CL0007- CL0021- PF03725

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6A5KTN3 264-916 GDTTVLCTAVAAKAPKPGVDFFPLTVNYQEKAFAAGKIPGGFFKREGRPTEKETLVSRLIDRPIRPLFADGFRNETQVVCTVLSHDL…
A0A2G9YCS3 22-553 FAGRANGAVTVQYGDTLILATAVMAKKPREEVDYMPLMVDYEEKLYAAGKIKGSRWVKREGRPSDEAILTGRLIDRCLRPLFDERIR…
A0A7E4SGL6 336-1007 None
A0A843U7B0 27-716 None
A0A6F9C5Z8 5-486 None
I0YP49 30-694 None
A0A1Q7C8B0 8-669 None
A0A4Y7L9F5 73-547 None
A0A4Y7IJ97 46-728 None
A0A2R2MQD2 16-647 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.